En-CA SOLUTION contains two different types of antibiotics and one anti-viral agent. Combination treatment with Amantadine (anti-viral agent) provide greater protection against lethal infection. Colistin is effective against most Gram-negative bacilli It remains one of the last-resort antibiotics for multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter Enrofloxcin is a bactericidal agent with susceptible bacteria cell death occurring within 20–30 minutes of exposure.